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Enhancement of dissolution profile by solid dispersion (kneading) technique
This article investigates enhancement of the dissolution profile of valdecoxib using solid dispersion with PVP. The article also describes the preparation of fast-dissolving tablets of valdecoxib by using a high amount of superdisintegrants. A phase solubility method was used to evaluate the effect...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750510/ https://ncbi.nlm.nih.gov/pubmed/17025249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070368 |
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