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Dissolution enhancement of efavirenz by solid dispersion and PEGylation techniques
BACKGROUND: Efavirenz is the preferred nonnucleotide reverse transcriptase inhibitor for first-line antiretroviral treatment in many countries. It is orally active and is specific for human immunodeficiency virus type 1. Its effectiveness can be attributed to its long half-life, which is 52–76 h aft...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications & Media Pvt Ltd
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465113/ https://ncbi.nlm.nih.gov/pubmed/23071917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.76726 |
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