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Structural biology of telomeres and telomerase

Telomeres are protein–DNA complexes that protect chromosome ends from illicit ligation and resection. Telomerase is a ribonucleoprotein enzyme that synthesizes telomeric DNA to counter telomere shortening. Human telomeres are composed of complexes between telomeric DNA and a six-protein complex know...

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Publicat a:Cell Mol Life Sci
Autors principals: Smith, Eric M., Pendlebury, Devon F., Nandakumar, Jayakrishnan
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986361/
https://ncbi.nlm.nih.gov/pubmed/31728577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03369-x
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