Caricamento...

Mutations in Ribosomal Protein RplA or Treatment with Ribosomal Acting Antibiotics Activates Production of Aminoglycoside Efflux Pump SmeYZ in Stenotrophomonas maltophilia

Aminoglycoside resistance in Stenotrophomonas maltophilia is multifactorial, but the most significant mechanism is overproduction of the SmeYZ efflux system. By studying laboratory-selected mutants and clinical isolates, we show here that damage to the 50S ribosomal protein L1 (RplA) activates SmeYZ...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Calvopiña, Karina, Dulyayangkul, Punyawee, Avison, Matthew B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985731/
https://ncbi.nlm.nih.gov/pubmed/31712205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01524-19
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !