In Vitro Derivation of Fluoroquinolone-Resistant Mutants from Multiple Lineages of Haemophilus influenzae and Identification of Mutations Associated with Fluoroquinolone Resistance

Haemophilus influenzae is a pathogenic bacterium that causes respiratory and otolaryngological infections. The increasing prevalence of β-lactamase–negative high-level ampicillin-resistant H. influenzae (high-BLNAR) is a clinical concern. Fluoroquinolones are alternative agents to β-lactams. However...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Honda, Hiroyuki, Sato, Toyotaka, Shinagawa, Masaaki, Fukushima, Yukari, Nakajima, Chie, Suzuki, Yasuhiko, Kuronuma, Koji, Takahashi, Satoshi, Takahashi, Hiroki, Yokota, Shin-ichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985711/
https://ncbi.nlm.nih.gov/pubmed/31740553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01500-19
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