Contribution of Novel Amino Acid Alterations in PmrA or PmrB to Colistin Resistance in mcr-Negative Escherichia coli Clinical Isolates, Including Major Multidrug-Resistant Lineages O25b:H4-ST131-H30Rx and Non-x

Colistin is a last-line drug for multidrug-resistant Gram-negative bacteria. We previously reported four plasmid-mediated colistin resistance (mcr) gene-negative colistin-resistant Escherichia coli clinical isolates, including the major pathogenic and fluoroquinolone-resistant strains O25b:H4-ST131-...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Sato, Toyotaka, Shiraishi, Tsukasa, Hiyama, Yoshiki, Honda, Hiroyuki, Shinagawa, Masaaki, Usui, Masaru, Kuronuma, Koji, Masumori, Naoya, Takahashi, Satoshi, Tamura, Yutaka, Yokota, Shin-ichi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125499/
https://ncbi.nlm.nih.gov/pubmed/29914952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00864-18
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