Cyclooxygenase-2 Induced the β-Amyloid Protein Deposition and Neuronal Apoptosis Via Upregulating the Synthesis of Prostaglandin E(2) and 15-Deoxy-Δ(12,14)-prostaglandin J(2)

Elevated levels of cyclooxygenase-2 (COX-2) and prostaglandins (PGs) have been shown to be involved in the pathogenesis of Alzheimer’s disease. Analysis of the underlying mechanisms elucidated a function of sequential PGE(2) and PGD(2) synthesis in regulating β-amyloid protein (Aβ) deposition by mod...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurotherapeutics
Egile Nagusiak: Guan, Pei-Pei, Liang, Yun-Yue, Cao, Long-Long, Yu, Xin, Wang, Pu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer International Publishing 2019
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985346/
https://ncbi.nlm.nih.gov/pubmed/31392591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00770-z
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