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Alternative Lengthening of Telomeres in Pediatric Cancer: Mechanisms to Therapies
Achieving replicative immortality is a crucial step in tumorigenesis and requires both bypassing cell cycle checkpoints and the extension of telomeres, sequences that protect the distal ends of chromosomes during replication. In the majority of cancers this is achieved through the enzyme telomerase,...
Gorde:
| Argitaratua izan da: | Front Oncol |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Frontiers Media S.A.
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985284/ https://ncbi.nlm.nih.gov/pubmed/32039009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01518 |
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