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Integrative analysis reveals RNA G-quadruplexes in UTRs are selectively constrained and enriched for functional associations
G-quadruplex (G4) sequences are abundant in untranslated regions (UTRs) of human messenger RNAs, but their functional importance remains unclear. By integrating multiple sources of genetic and genomic data, we show that putative G-quadruplex forming sequences (pG4) in 5’ and 3’ UTRs are selectively...
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| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985247/ https://ncbi.nlm.nih.gov/pubmed/31988292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14404-y |
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