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Integrative analysis reveals RNA G-quadruplexes in UTRs are selectively constrained and enriched for functional associations
G-quadruplex (G4) sequences are abundant in untranslated regions (UTRs) of human messenger RNAs, but their functional importance remains unclear. By integrating multiple sources of genetic and genomic data, we show that putative G-quadruplex forming sequences (pG4) in 5’ and 3’ UTRs are selectively...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985247/ https://ncbi.nlm.nih.gov/pubmed/31988292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14404-y |
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