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An RNA G-quadruplex in the 5′ UTR of the NRAS proto-oncogene modulates translation

Guanine-rich nucleic acid sequences can adopt noncanonical four-stranded secondary structures called guanine (G)-quadruplexes1. Bioinformatics analysis suggests that G-quadruplex motifs are prevalent in genomes2, which raises the need to elucidate their function. There is now evidence for the existe...

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Detalhes bibliográficos
Main Authors: Kumari, Sunita, Bugaut, Anthony, Huppert, Julian L, Balasubramanian, Shankar
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206252/
https://ncbi.nlm.nih.gov/pubmed/17322877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio864
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