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Position and Stability Are Determining Factors for Translation Repression by an RNA G-Quadruplex-Forming Sequence within the 5′ UTR of the NRAS Proto-oncogene
Nucleic acid secondary structures in the 5′ untranslated regions (UTRs) of mRNAs have been shown to play a critical role in translation regulation. We recently demonstrated that a naturally occurring, conserved, and stable RNA G-quadruplex element (5′-GGGAGGGGCGGGUCUGGG-3′), located close to the 5′...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746962/ https://ncbi.nlm.nih.gov/pubmed/18991403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8010797 |
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