Lymphatic endothelial cells prime naïve CD8(+) T cells into memory cells under steady-state conditions

Lymphatic endothelial cells (LECs) chemoattract naïve T cells and promote their survival in the lymph nodes, and can cross-present antigens to naïve CD8(+) T cells to drive their proliferation despite lacking key costimulatory molecules. However, the functional consequence of LEC priming of CD8(+) T...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Vokali, Efthymia, Yu, Shann S., Hirosue, Sachiko, Rinçon-Restrepo, Marcela, V. Duraes, Fernanda, Scherer, Stefanie, Corthésy-Henrioud, Patricia, Kilarski, Witold W., Mondino, Anna, Zehn, Dietmar, Hugues, Stéphanie, Swartz, Melody A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985113/
https://ncbi.nlm.nih.gov/pubmed/31988323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14127-9
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