Adjuvant-free immunization with infective filarial larvae as lymphatic homing antigen carriers

Controlled infection with intestinal nematodes has therapeutic potential for preventing the symptoms of allergic and autoimmune diseases. Here, we engineered larvae of the filarial nematode Litomosoides sigmodontis as a vaccine strategy to induce adaptive immunity against a foreign, crosslinked prot...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Card, Catherine, Wilson, David S., Hirosue, Sachiko, Rincon-Restrepo, Marcela, de Titta, Alexandre, Güç, Esra, Martin, Coralie, Bain, Odile, Swartz, Melody A., Kilarski, Witold W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978462/
https://ncbi.nlm.nih.gov/pubmed/31974398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57995-8
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