Adjuvant-free immunization with infective filarial larvae as lymphatic homing antigen carriers

Controlled infection with intestinal nematodes has therapeutic potential for preventing the symptoms of allergic and autoimmune diseases. Here, we engineered larvae of the filarial nematode Litomosoides sigmodontis as a vaccine strategy to induce adaptive immunity against a foreign, crosslinked prot...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Card, Catherine, Wilson, David S., Hirosue, Sachiko, Rincon-Restrepo, Marcela, de Titta, Alexandre, Güç, Esra, Martin, Coralie, Bain, Odile, Swartz, Melody A., Kilarski, Witold W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978462/
https://ncbi.nlm.nih.gov/pubmed/31974398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57995-8
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