Adjuvant-free immunization with infective filarial larvae as lymphatic homing antigen carriers

Controlled infection with intestinal nematodes has therapeutic potential for preventing the symptoms of allergic and autoimmune diseases. Here, we engineered larvae of the filarial nematode Litomosoides sigmodontis as a vaccine strategy to induce adaptive immunity against a foreign, crosslinked prot...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Card, Catherine, Wilson, David S., Hirosue, Sachiko, Rincon-Restrepo, Marcela, de Titta, Alexandre, Güç, Esra, Martin, Coralie, Bain, Odile, Swartz, Melody A., Kilarski, Witold W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978462/
https://ncbi.nlm.nih.gov/pubmed/31974398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57995-8
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