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Adjuvant-free immunization with infective filarial larvae as lymphatic homing antigen carriers
Controlled infection with intestinal nematodes has therapeutic potential for preventing the symptoms of allergic and autoimmune diseases. Here, we engineered larvae of the filarial nematode Litomosoides sigmodontis as a vaccine strategy to induce adaptive immunity against a foreign, crosslinked prot...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6978462/ https://ncbi.nlm.nih.gov/pubmed/31974398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57995-8 |
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