Transcriptome analysis reveals overlap in fusion genes in a phase I clinical cohort of TNBC and HGSOC patients treated with buparlisib and olaparib

PURPOSE: Fusion genes can be therapeutically relevant if they result in constitutive activation of oncogenes or repression of tumor suppressors. However, the prevalence and role of fusion genes in female cancers remain largely unexplored. Here, we investigate the fusion gene landscape in triple-nega...

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Publicat a:J Cancer Res Clin Oncol
Autors principals: Eismann, Julia, Heng, Yujing J., Waldschmidt, Johannes M., Vlachos, Ioannis S., Gray, Kathryn P., Matulonis, Ursula A., Konstantinopoulos, Panagiotis A., Murphy, Charles J., Nabavi, Sheida, Wulf, Gerburg M.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2019
Matèries:
Original Article – Clinical Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985087/
https://ncbi.nlm.nih.gov/pubmed/31745703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-019-03078-9
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