Transcriptome analysis reveals overlap in fusion genes in a phase I clinical cohort of TNBC and HGSOC patients treated with buparlisib and olaparib

PURPOSE: Fusion genes can be therapeutically relevant if they result in constitutive activation of oncogenes or repression of tumor suppressors. However, the prevalence and role of fusion genes in female cancers remain largely unexplored. Here, we investigate the fusion gene landscape in triple-nega...

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Dettagli Bibliografici
Pubblicato in:J Cancer Res Clin Oncol
Autori principali: Eismann, Julia, Heng, Yujing J., Waldschmidt, Johannes M., Vlachos, Ioannis S., Gray, Kathryn P., Matulonis, Ursula A., Konstantinopoulos, Panagiotis A., Murphy, Charles J., Nabavi, Sheida, Wulf, Gerburg M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2019
Soggetti:
Original Article – Clinical Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985087/
https://ncbi.nlm.nih.gov/pubmed/31745703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-019-03078-9
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