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Deletion of donor-reactive T cell clones following human liver transplantation

We recently developed a high throughput T cell receptor β chain (TCRβ) sequencing-based approach to identifying and tracking donor-reactive T cells. To address the role of clonal deletion in liver allograft tolerance, we applied this method in samples from a recent randomized study, ITN030ST, in whi...

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Detalles Bibliográficos
Publicado en:Am J Transplant
Main Authors: Savage, Thomas M., Shonts, Brittany A., Lau, Saiping, Obradovic, Aleksandar, Robins, Harlan, Shaked, Abraham, Shen, Yufeng, Sykes, Megan
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984984/
https://ncbi.nlm.nih.gov/pubmed/31509321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15592
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