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Regulation of lysosome integrity and lysophagy by the ubiquitin-conjugating enzyme UBE2QL1

Lysosomal membrane permeabilization or full rupture of lysosomes is a common and severe stress condition that is relevant for degenerative disease, infection and cancer. Cells respond with extensive ubiquitination of damaged lysosomes, which triggers selective macroautophagy/autophagy of the whole o...

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Publicat a:Autophagy
Autors principals: Kravic, Bojana, Behrends, Christian, Meyer, Hemmo
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984614/
https://ncbi.nlm.nih.gov/pubmed/31679434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1687217
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