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Stochastic Gene Expression Influences the Selection of Antibiotic Resistance Mutations
Bacteria can resist antibiotics by expressing enzymes that remove or deactivate drug molecules. Here, we study the effects of gene expression stochasticity on efflux and enzymatic resistance. We construct an agent-based model that stochastically simulates multiple biochemical processes in the cell a...
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| Publicado no: | Mol Biol Evol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6984361/ https://ncbi.nlm.nih.gov/pubmed/31504754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz199 |
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