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Stochastic Gene Expression Influences the Selection of Antibiotic Resistance Mutations
Bacteria can resist antibiotics by expressing enzymes that remove or deactivate drug molecules. Here, we study the effects of gene expression stochasticity on efflux and enzymatic resistance. We construct an agent-based model that stochastically simulates multiple biochemical processes in the cell a...
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| Pubblicato in: | Mol Biol Evol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6984361/ https://ncbi.nlm.nih.gov/pubmed/31504754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz199 |
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