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Stochastic Interplay between Mutation and Recombination during the Acquisition of Drug Resistance Mutations in Human Immunodeficiency Virus Type 1

The emergence of drug resistance mutations in human immunodeficiency virus (HIV) has been a major setback in the treatment of infected patients. Besides the high mutation rate, recombination has been conjectured to have an important impact on the emergence of drug resistance. Population genetic theo...

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Detalhes bibliográficos
Main Authors: Althaus, Christian L., Bonhoeffer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1262575/
https://ncbi.nlm.nih.gov/pubmed/16227277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.21.13572-13578.2005
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