Bisulfite-free and base-resolution analysis of 5-methylcytidine and 5-hydroxymethylcytidine in RNA with peroxotungstate

5-Methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), two of the best-studied DNA modifications, play crucial roles in normal development and disease in mammals. Although 5-methylcytidine (m(5)C) and 5-hydroxymethylcytidine (hm(5)C) have also been identified in RNA, their distribution and biolo...

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Detalles Bibliográficos
Publicado en:Chem Commun (Camb)
Autores principales: Yuan, Fang, Bi, Ying, Siejka-Zielinska, Paulina, Zhou, Ying-Lin, Zhang, Xin-Xiang, Song, Chun-Xiao
Formato: Artigo
Lenguaje:Inglês
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984333/
https://ncbi.nlm.nih.gov/pubmed/30723849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc00274j
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