Infection-induced signals generated at the plasma membrane epigenetically regulate Wnt signaling in vitro and in vivo

Wnt signaling regulates immunomodulatory functions during infection and inflammation. Employing NCCIT and HCT116 cells, having high endogenous Wnt signaling, we observed elevated levels of low-density lipoprotein receptor–related protein 5/6 (LRP5/6) and Frizzled class receptor 10 (FZD10) and increa...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ahmed, Ishfaq, Roy, Badal Chandra, Rao Jakkula, Laxmi Uma Maheswar, Subramaniam, Dharmalingam, Dandawate, Prasad, Anant, Shrikant, Sampath, Venkatesh, Umar, Shahid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983838/
https://ncbi.nlm.nih.gov/pubmed/31836665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010285
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