Infection-induced signals generated at the plasma membrane epigenetically regulate Wnt signaling in vitro and in vivo

Wnt signaling regulates immunomodulatory functions during infection and inflammation. Employing NCCIT and HCT116 cells, having high endogenous Wnt signaling, we observed elevated levels of low-density lipoprotein receptor–related protein 5/6 (LRP5/6) and Frizzled class receptor 10 (FZD10) and increa...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Ahmed, Ishfaq, Roy, Badal Chandra, Rao Jakkula, Laxmi Uma Maheswar, Subramaniam, Dharmalingam, Dandawate, Prasad, Anant, Shrikant, Sampath, Venkatesh, Umar, Shahid
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983838/
https://ncbi.nlm.nih.gov/pubmed/31836665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010285
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