Infection-induced signals generated at the plasma membrane epigenetically regulate Wnt signaling in vitro and in vivo

Wnt signaling regulates immunomodulatory functions during infection and inflammation. Employing NCCIT and HCT116 cells, having high endogenous Wnt signaling, we observed elevated levels of low-density lipoprotein receptor–related protein 5/6 (LRP5/6) and Frizzled class receptor 10 (FZD10) and increa...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Ahmed, Ishfaq, Roy, Badal Chandra, Rao Jakkula, Laxmi Uma Maheswar, Subramaniam, Dharmalingam, Dandawate, Prasad, Anant, Shrikant, Sampath, Venkatesh, Umar, Shahid
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2020
Aiheet:
Signal Transduction
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983838/
https://ncbi.nlm.nih.gov/pubmed/31836665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010285
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