Infection-induced signals generated at the plasma membrane epigenetically regulate Wnt signaling in vitro and in vivo

Wnt signaling regulates immunomodulatory functions during infection and inflammation. Employing NCCIT and HCT116 cells, having high endogenous Wnt signaling, we observed elevated levels of low-density lipoprotein receptor–related protein 5/6 (LRP5/6) and Frizzled class receptor 10 (FZD10) and increa...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Ahmed, Ishfaq, Roy, Badal Chandra, Rao Jakkula, Laxmi Uma Maheswar, Subramaniam, Dharmalingam, Dandawate, Prasad, Anant, Shrikant, Sampath, Venkatesh, Umar, Shahid
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983838/
https://ncbi.nlm.nih.gov/pubmed/31836665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010285
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