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Senescent mesenchymal stem cells remodel extracellular matrix driving breast cancer cells to a more-invasive phenotype

Mesenchymal stem cells (MSCs) are essential for the regenerative process; however, biological aging and environmental stress can induce senescence – an irreversible state of growth arrest – that not only affects the behavior of cells but also disrupts their ability to restore tissue integrity. While...

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Dades bibliogràfiques
Publicat a:J Cell Sci
Autors principals: Ghosh, Deepraj, Mejia Pena, Carolina, Quach, Nhat, Xuan, Botai, Lee, Amy H., Dawson, Michelle R.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983709/
https://ncbi.nlm.nih.gov/pubmed/31932504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.232470
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