An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness

It is anticipated that bioactive fragments of the extracellular matrix (matrikines) can influence the development and progression of chronic diseases. The enzyme leukotriene A(4) hydrolase (LTA(4)H) mediates opposing proinflammatory and anti-inflammatory activities, through the generation of leukotr...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Patel, Dhiren F., Peiró, Teresa, Shoemark, Amelia, Akthar, Samia, Walker, Simone A., Grabiec, Aleksander M., Jackson, Patricia L., Hussell, Tracy, Gaggar, Amit, Xu, Xin, Trevor, Jennifer L., Li, Jindong, Steele, Chad, Tavernier, Gael, Blalock, J. Edwin, Niven, Robert M., Gregory, Lisa G., Simpson, Angela, Lloyd, Clare M., Snelgrove, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342449/
https://ncbi.nlm.nih.gov/pubmed/30135247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaq0693
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