An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness

It is anticipated that bioactive fragments of the extracellular matrix (matrikines) can influence the development and progression of chronic diseases. The enzyme leukotriene A(4) hydrolase (LTA(4)H) mediates opposing proinflammatory and anti-inflammatory activities, through the generation of leukotr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Transl Med
Päätekijät: Patel, Dhiren F., Peiró, Teresa, Shoemark, Amelia, Akthar, Samia, Walker, Simone A., Grabiec, Aleksander M., Jackson, Patricia L., Hussell, Tracy, Gaggar, Amit, Xu, Xin, Trevor, Jennifer L., Li, Jindong, Steele, Chad, Tavernier, Gael, Blalock, J. Edwin, Niven, Robert M., Gregory, Lisa G., Simpson, Angela, Lloyd, Clare M., Snelgrove, Robert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342449/
https://ncbi.nlm.nih.gov/pubmed/30135247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaq0693
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