Repeated methamphetamine and modafinil induce differential cognitive effects and specific histone acetylation and DNA methylation profiles in the mouse medial prefrontal cortex.

Methamphetamine (METH) and modafinil are psychostimulants with different long-term cognitive profiles: METH is addictive and leads to cognitive decline, whereas modafinil has little abuse liability and is a cognitive enhancer. Increasing evidence implicates epigenetic mechanisms of gene regulation b...

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Bibliografiska uppgifter
I publikationen:Prog Neuropsychopharmacol Biol Psychiatry
Huvudupphovsmän: González, Betina, Jayanthi, Subramaniam, Gomez, Natalia, Torres, Oscar V., Sosa, Máximo H., Bernardi, Alejandra, Urbano, Francisco J., García-Rill, Edgar, Cadet, Jean-Lud, Bisagno, Verónica
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983674/
https://ncbi.nlm.nih.gov/pubmed/29247759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2017.12.009
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