Repeated methamphetamine and modafinil induce differential cognitive effects and specific histone acetylation and DNA methylation profiles in the mouse medial prefrontal cortex.

Methamphetamine (METH) and modafinil are psychostimulants with different long-term cognitive profiles: METH is addictive and leads to cognitive decline, whereas modafinil has little abuse liability and is a cognitive enhancer. Increasing evidence implicates epigenetic mechanisms of gene regulation b...

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Bibliografske podrobnosti
izdano v:Prog Neuropsychopharmacol Biol Psychiatry
Main Authors: González, Betina, Jayanthi, Subramaniam, Gomez, Natalia, Torres, Oscar V., Sosa, Máximo H., Bernardi, Alejandra, Urbano, Francisco J., García-Rill, Edgar, Cadet, Jean-Lud, Bisagno, Verónica
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983674/
https://ncbi.nlm.nih.gov/pubmed/29247759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2017.12.009
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