Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans

Feline infectious peritonitis virus (FIPV) is an alphacoronavirus that causes a nearly 100% mortality rate without effective treatment. Here we report a 3.3-Å cryoelectron microscopy (cryo-EM) structure of the serotype I FIPV spike (S) protein, which is responsible for host recognition and viral ent...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yang, Tzu-Jing, Chang, Yen-Chen, Ko, Tzu-Ping, Draczkowski, Piotr, Chien, Yu-Chun, Chang, Yuan-Chih, Wu, Kuen-Phon, Khoo, Kay-Hooi, Chang, Hui-Wen, Hsu, Shang-Te Danny
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983407/
https://ncbi.nlm.nih.gov/pubmed/31900356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908898117
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