Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice

Carbon dioxide (CO(2)), the major product of metabolism, has a strong impact on cerebral blood vessels, a phenomenon known as cerebrovascular reactivity. Several vascular risk factors such as hypertension or diabetes dampen this response, making cerebrovascular reactivity a useful diagnostic marker...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wenzel, Jan, Hansen, Cathrin E., Bettoni, Carla, Vogt, Miriam A., Lembrich, Beate, Natsagdorj, Rentsenkhand, Huber, Gianna, Brands, Josefine, Schmidt, Kjestine, Assmann, Julian C., Stölting, Ines, Saar, Kathrin, Sedlacik, Jan, Fiehler, Jens, Ludewig, Peter, Wegmann, Michael, Feller, Nina, Richter, Marius, Müller-Fielitz, Helge, Walther, Thomas, König, Gabriele M., Kostenis, Evi, Raasch, Walter, Hübner, Norbert, Gass, Peter, Offermanns, Stefan, de Wit, Cor, Wagner, Carsten A., Schwaninger, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983400/
https://ncbi.nlm.nih.gov/pubmed/31896584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907467117
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