Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice

Carbon dioxide (CO(2)), the major product of metabolism, has a strong impact on cerebral blood vessels, a phenomenon known as cerebrovascular reactivity. Several vascular risk factors such as hypertension or diabetes dampen this response, making cerebrovascular reactivity a useful diagnostic marker...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Wenzel, Jan, Hansen, Cathrin E., Bettoni, Carla, Vogt, Miriam A., Lembrich, Beate, Natsagdorj, Rentsenkhand, Huber, Gianna, Brands, Josefine, Schmidt, Kjestine, Assmann, Julian C., Stölting, Ines, Saar, Kathrin, Sedlacik, Jan, Fiehler, Jens, Ludewig, Peter, Wegmann, Michael, Feller, Nina, Richter, Marius, Müller-Fielitz, Helge, Walther, Thomas, König, Gabriele M., Kostenis, Evi, Raasch, Walter, Hübner, Norbert, Gass, Peter, Offermanns, Stefan, de Wit, Cor, Wagner, Carsten A., Schwaninger, Markus
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2020
Ábhair:
PNAS Plus
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983400/
https://ncbi.nlm.nih.gov/pubmed/31896584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907467117
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