A Novel Gel-Forming Solution Based on PEG-DSPE/Solutol HS 15 Mixed Micelles and Gellan Gum for Ophthalmic Delivery of Curcumin

Curcumin (Cur) is a naturally hydrophobic polyphenol with potential pharmacological properties. However, the poor aqueous solubility and low bioavailability of curcumin limits its ocular administration. Thus, the aim of this study was to prepare a mixed micelle in situ gelling system of curcumin (Cu...

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Udgivet i:Molecules
Main Authors: Sai, Na, Dong, Xiaoxv, Huang, Pingqing, You, Longtai, Yang, Chunjing, Liu, Yi, Wang, Wenping, Wu, Huimin, Yu, Yingchao, Du, Yuanyuan, Leng, Xin, Yin, Xingbin, Qu, Changhai, Ni, Jian
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983186/
https://ncbi.nlm.nih.gov/pubmed/31878332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25010081
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