Human Molecular Chaperone Hsp60 and Its Apical Domain Suppress Amyloid Fibril Formation of α-Synuclein

Heat shock proteins play roles in assisting other proteins to fold correctly and in preventing the aggregation and accumulation of proteins in misfolded conformations. However, the process of aging significantly degrades this ability to maintain protein homeostasis. Consequently, proteins with incor...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Yamamoto, Hanae, Fukui, Naoya, Adachi, Mayuka, Saiki, Eiichi, Yamasaki, Anna, Matsumura, Rio, Kuroyanagi, Daichi, Hongo, Kunihiro, Mizobata, Tomohiro, Kawata, Yasushi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982183/
https://ncbi.nlm.nih.gov/pubmed/31861692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010047
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