Human Molecular Chaperone Hsp60 and Its Apical Domain Suppress Amyloid Fibril Formation of α-Synuclein

Heat shock proteins play roles in assisting other proteins to fold correctly and in preventing the aggregation and accumulation of proteins in misfolded conformations. However, the process of aging significantly degrades this ability to maintain protein homeostasis. Consequently, proteins with incor...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yamamoto, Hanae, Fukui, Naoya, Adachi, Mayuka, Saiki, Eiichi, Yamasaki, Anna, Matsumura, Rio, Kuroyanagi, Daichi, Hongo, Kunihiro, Mizobata, Tomohiro, Kawata, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982183/
https://ncbi.nlm.nih.gov/pubmed/31861692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010047
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