Cargando...

Mediation Analysis Supports a Causal Relationship between Maternal Hyperglycemia and Placental DNA Methylation Variations at the Leptin Gene Locus and Cord Blood Leptin Levels

Changes in fetal DNA methylation (DNAm) of the leptin (LEP) gene have been associated with exposure to maternal hyperglycemia, but their links with childhood obesity risk are still unclear. We investigated the association between maternal hyperglycemia, placental LEP DNAm (25 5′-C-phosphate-G-3′ (Cp...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Gagné-Ouellet, Valérie, Breton, Edith, Thibeault, Kathrine, Fortin, Carol-Ann, Cardenas, Andres, Guérin, Renée, Perron, Patrice, Hivert, Marie-France, Bouchard, Luigi
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982090/
https://ncbi.nlm.nih.gov/pubmed/31947745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010329
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!