Mendelian randomization supports causality between maternal hyperglycemia and epigenetic regulation of leptin gene in newborns

Leptin is an adipokine that acts in the central nervous system and regulates energy balance. Animal models and human observational studies have suggested that leptin surge in the perinatal period has a critical role in programming long-term risk of obesity. In utero exposure to maternal hyperglycemi...

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Detalles Bibliográficos
Publicado en:Epigenetics
Autores principales: Allard, C, Desgagné, V, Patenaude, J, Lacroix, M, Guillemette, L, Battista, MC, Doyon, M, Ménard, J, Ardilouze, JL, Perron, P, Bouchard, L, Hivert, MF
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622547/
https://ncbi.nlm.nih.gov/pubmed/25800063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1029700
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