Mendelian randomization supports causality between maternal hyperglycemia and epigenetic regulation of leptin gene in newborns

Leptin is an adipokine that acts in the central nervous system and regulates energy balance. Animal models and human observational studies have suggested that leptin surge in the perinatal period has a critical role in programming long-term risk of obesity. In utero exposure to maternal hyperglycemi...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Allard, C, Desgagné, V, Patenaude, J, Lacroix, M, Guillemette, L, Battista, MC, Doyon, M, Ménard, J, Ardilouze, JL, Perron, P, Bouchard, L, Hivert, MF
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622547/
https://ncbi.nlm.nih.gov/pubmed/25800063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1029700
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