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Structural Characterization of the CD44 Stem Region for Standard and Cancer-Associated Isoforms

CD44 is widely expressed in most vertebrate cells, whereas the expression of CD44v6 is restricted to only a few tissues and has been considered to be associated with tumor progression and metastasis. Thus, CD44v6 has been recognized as a promising prognostic biomarker and therapeutic target for vari...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Chen, Kun-Lin, Li, Deng, Lu, Ting-Xuan, Chang, Shu-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982006/
https://ncbi.nlm.nih.gov/pubmed/31947887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010336
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