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Feedback Regulation of Syk by Protein Kinase C in Human Platelets

The spleen tyrosine kinase (Syk) is essential for immunoreceptor tyrosine-based activation motif (ITAM)-dependent platelet activation, and it is stimulated by Src-family kinase (SFK)-/Syk-mediated phosphorylation of Y352 (interdomain-B) and Y525/526 (kinase domain). Additional sites for Syk phosphor...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Makhoul, Stephanie, Dorschel, Stephanie, Gambaryan, Stepan, Walter, Ulrich, Jurk, Kerstin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981976/
https://ncbi.nlm.nih.gov/pubmed/31881809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010176
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