Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia

Myelodysplastic syndrome (MDS) defines a group of heterogeneous hematologic malignancies that often progresses to acute myeloid leukemia (AML). The leading treatment for high-risk MDS patients is azacitidine (Aza, Vidaza(®)), but a significant proportion of patients are refractory and all patients e...

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Udgivet i:Int J Mol Sci
Main Authors: Cluzeau, Thomas, Furstoss, Nathan, Savy, Coline, El Manaa, Wejdane, Zerhouni, Marwa, Blot, Lauriane, Calleja, Anne, Dufies, Maeva, Dubois, Alix, Ginet, Clemence, Mounier, Nicolas, Garnier, Georges, Raynaud, Sophie, Rohrlich, Pierre Simon, Peterlin, Pierre, Stamatoullas, Aspasia, Chermat, Fatiha, Fenaux, Pierre, Jacquel, Arnaud, Robert, Guillaume, Auberger, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981810/
https://ncbi.nlm.nih.gov/pubmed/31881723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010164
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