Gene Copy Number and Post-Transductional Mechanisms Regulate TRAP1 Expression in Human Colorectal Carcinomas

Tumor Necrosis Factor Receptor-Associated Protein 1 (TRAP1) is a heat shock protein 90 (HSP90) molecular chaperone overexpressed in 60–70% human colorectal carcinomas (CRCs) and the co-upregulation of TRAP1 and associated 6-related proteins identifies metastatic CRCs with poor prognosis. Since the m...

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Publicat a:Int J Mol Sci
Autors principals: Pietrafesa, Michele, Maddalena, Francesca, Possidente, Luciana, Condelli, Valentina, Zoppoli, Pietro, Li Bergolis, Valeria, Rodriquenz, Maria Grazia, Aieta, Michele, Vita, Giulia, Esposito, Franca, Landriscina, Matteo
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981705/
https://ncbi.nlm.nih.gov/pubmed/31878280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010145
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