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The Evolving Protein Engineering in the Design of Chimeric Antigen Receptor T Cells

The clinical success of chimeric antigen receptor (CAR) T cell immunotherapy in the treatment of haematological cancers has encouraged the extensive development of CAR design to improve their function and increase their applicability. Advancements in protein engineering have seen modifications to bo...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Hughes-Parry, Hannah E., Cross, Ryan S., Jenkins, Misty R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981602/
https://ncbi.nlm.nih.gov/pubmed/31892219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010204
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