Defects in G-Actin Incorporation into Filaments in Myoblasts Derived from Dysferlinopathy Patients Are Restored by Dysferlin C2 Domains

Dysferlin is a transmembrane C-2 domain-containing protein involved in vesicle trafficking and membrane remodeling in skeletal muscle cells. However, the mechanism by which dysferlin regulates these cellular processes remains unclear. Since actin dynamics is critical for vesicle trafficking and memb...

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Publicado en:Int J Mol Sci
Main Authors: Báez-Matus, Ximena, Figueroa-Cares, Cindel, Gónzalez-Jamett, Arlek M., Almarza-Salazar, Hugo, Arriagada, Christian, Maldifassi, María Constanza, Guerra, María José, Mouly, Vincent, Bigot, Anne, Caviedes, Pablo, Cárdenas, Ana M.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981584/
https://ncbi.nlm.nih.gov/pubmed/31861684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010037
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