The absence of dysferlin induces the expression of functional connexin-based hemichannels in human myotubes

BACKGROUND: Mutations in the gene encoding for dysferlin cause recessive autosomal muscular dystrophies called dysferlinopathies. These mutations induce several alterations in skeletal muscles, including, inflammation, increased membrane permeability and cell death. Despite the fact that the etiolog...

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Udgivet i:BMC Cell Biol
Main Authors: Cea, Luis A., Bevilacqua, Jorge A., Arriagada, Christian, Cárdenas, Ana María, Bigot, Anne, Mouly, Vincent, Sáez, Juan C., Caviedes, Pablo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896263/
https://ncbi.nlm.nih.gov/pubmed/27229680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-016-0096-6
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