RCAN1 Knockdown Reverts Defects in the Number of Calcium-Induced Exocytotic Events in a Cellular Model of Down Syndrome

In humans, Down Syndrome (DS) is a condition caused by partial or full trisomy of chromosome 21. Genes present in the DS critical region can result in excess gene dosage, which at least partially can account for DS phenotype. Although regulator of calcineurin 1 (RCAN1) belongs to this region and its...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Vásquez-Navarrete, Jacqueline, Martínez, Agustín D., Ory, Stéphane, Baéz-Matus, Ximena, González-Jamett, Arlek M., Brauchi, Sebastián, Caviedes, Pablo, Cárdenas, Ana M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043644/
https://ncbi.nlm.nih.gov/pubmed/30034324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00189
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