RCAN1 Knockdown Reverts Defects in the Number of Calcium-Induced Exocytotic Events in a Cellular Model of Down Syndrome

In humans, Down Syndrome (DS) is a condition caused by partial or full trisomy of chromosome 21. Genes present in the DS critical region can result in excess gene dosage, which at least partially can account for DS phenotype. Although regulator of calcineurin 1 (RCAN1) belongs to this region and its...

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Dettagli Bibliografici
Pubblicato in:Front Cell Neurosci
Autori principali: Vásquez-Navarrete, Jacqueline, Martínez, Agustín D., Ory, Stéphane, Baéz-Matus, Ximena, González-Jamett, Arlek M., Brauchi, Sebastián, Caviedes, Pablo, Cárdenas, Ana M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043644/
https://ncbi.nlm.nih.gov/pubmed/30034324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00189
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