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Binding of HasA by its transmembrane receptor HasR follows a conformational funnel mechanism
HasR in the outer membrane of Serratia marcescens binds secreted, heme-loaded HasA and translocates the heme to the periplasm to satisfy the cell’s demand for iron. The previously published crystal structure of the wild-type complex showed HasA in a very specific binding arrangement with HasR, apt t...
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| Publicado no: | Eur Biophys J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6981324/ https://ncbi.nlm.nih.gov/pubmed/31802151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-019-01411-1 |
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