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Mutagenesis and Molecular Modeling Reveal Three Key Extracellular Loops of the Membrane Receptor HasR That Are Involved in Hemophore HasA Binding

On the basis of the three-dimensional model of the heme/hemophore TonB-dependent outer membrane receptor HasR, mutants with six-residue deletions in the 11 putative extracellular loops were generated. Although all mutants continued to be active TonB-dependent heme transporters, mutations in three lo...

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Autori principali: Barjon, Clément, Wecker, Karine, Izadi-Pruneyre, Nadia, Delepelaire, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951882/
https://ncbi.nlm.nih.gov/pubmed/17483227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00251-07
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