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Targeting glutamine metabolism slows soft tissue sarcoma growth
Tumour cells frequently utilize glutamine to meet bioenergetic and biosynthetic demands of rapid cell growth. However, glutamine dependence can be highly variable between in vitro and in vivo settings, based on surrounding microenvironments and complex adaptive responses to glutamine deprivation. So...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6981153/ https://ncbi.nlm.nih.gov/pubmed/31980651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14374-1 |
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