IL-10 impairs local immune response in lung granulomas and lymph nodes during early Mycobacterium tuberculosis infection

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), continues to be a major global health problem. Lung granulomas are organized structures of host immune cells that function to contain the bacteria. Cytokine expression is a critical component of the protective immune response but inappro...

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Bibliografiska uppgifter
I publikationen:J Immunol
Huvudupphovsmän: Wong, Eileen A., Evans, Stephanie, Kraus, Carolyn R., Engelman, Kathleen D., Maiello, Pauline, Flores, Walter J., Cadena, Anthony M., Klein, Edwin, Thomas, Kayla, White, Alexander G., Causgrove, Chelsea, Stein, Brianne, Tomko, Jaime, Mattila, Joshua T., Gideon, Hannah, Lin, P. Ling, Reimann, Keith A., Kirschner, Denise E., Flynn, JoAnne L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981067/
https://ncbi.nlm.nih.gov/pubmed/31862711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901211
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