IL-10 impairs local immune response in lung granulomas and lymph nodes during early Mycobacterium tuberculosis infection

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), continues to be a major global health problem. Lung granulomas are organized structures of host immune cells that function to contain the bacteria. Cytokine expression is a critical component of the protective immune response but inappro...

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Udgivet i:J Immunol
Main Authors: Wong, Eileen A., Evans, Stephanie, Kraus, Carolyn R., Engelman, Kathleen D., Maiello, Pauline, Flores, Walter J., Cadena, Anthony M., Klein, Edwin, Thomas, Kayla, White, Alexander G., Causgrove, Chelsea, Stein, Brianne, Tomko, Jaime, Mattila, Joshua T., Gideon, Hannah, Lin, P. Ling, Reimann, Keith A., Kirschner, Denise E., Flynn, JoAnne L.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981067/
https://ncbi.nlm.nih.gov/pubmed/31862711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901211
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