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Predicting lymph node output efficiency using systems biology

Dendritic cells (DCs) capture pathogens and foreign antigen (Ag) in peripheral tissues and migrate to secondary lymphoid tissues, such as lymph nodes (LNs), where they present processed Ag as MHC-bound peptide (pMHC) to naïve T cells. Interactions between DCs and T cells result, over periods of hour...

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Détails bibliographiques
Auteurs principaux: Gong, Chang, Mattila, Joshua T., Miller, Mark, Flynn, JoAnne L., Linderman, Jennifer J., Kirschner, D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783027/
https://ncbi.nlm.nih.gov/pubmed/23816876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2013.06.016
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