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Predicting lymph node output efficiency using systems biology

Dendritic cells (DCs) capture pathogens and foreign antigen (Ag) in peripheral tissues and migrate to secondary lymphoid tissues, such as lymph nodes (LNs), where they present processed Ag as MHC-bound peptide (pMHC) to naïve T cells. Interactions between DCs and T cells result, over periods of hour...

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Detalhes bibliográficos
Main Authors: Gong, Chang, Mattila, Joshua T., Miller, Mark, Flynn, JoAnne L., Linderman, Jennifer J., Kirschner, D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783027/
https://ncbi.nlm.nih.gov/pubmed/23816876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2013.06.016
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